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U.S. and Iran Close in on Regional De-escalation Deal as Pakistan Intervenes

Negotiators move toward a 60-day framework involving uranium removal, sanctions waivers, and the reopening of global shipping lanes.

May 25, 2026 at 1:00 AM

Negotiations between the United States and Iran have reached a critical juncture, with President Donald Trump stating that a deal to end the regional conflict is 'largely negotiated' but not yet final. Secretary of State Marco Rubio echoed this cautious optimism, citing significant progress toward a framework that would address nuclear proliferation, maritime security, and economic sanctions. The emerging agreement reportedly hinges on a 60-day implementation period during which Iran would dispose of its highly enriched uranium stockpile—estimated by the IAEA at over 440 kilograms—likely by transferring it to a third country such as Russia. A significant shift in the diplomatic landscape is the active role of Pakistan as a back-channel mediator. Field Marshal Asim Munir recently concluded talks in Tehran, which Pakistani officials described as highly productive in bridging gaps between Washington and Tehran. Beyond nuclear inventory, the deal aims to stabilize global energy markets by reopening the Strait of Hormuz in exchange for the U.S. ending its blockade of Iranian ports and issuing oil export waivers. While the ceasefire established earlier this month continues to hold, President Trump has maintained a strategy of ambiguity, noting he remains '50/50' on the outcome to maintain maximum leverage. Iranian President Masoud Pezeshkian has maintained that while Iran does not seek nuclear weapons, it will not compromise on national dignity. The proposed package is expected to be comprehensive, potentially including a cessation of hostilities between Israel and Hezbollah and a mutual commitment to non-interference in regional domestic affairs.

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